منابع مشابه
From Tissues to Genomes
While it is always tempting to judge alleged scientific misconduct with the benefit of hindsight, it is not necessarily ethical or legal. Recently, much has been written on the multiple scientific and commercial uses of the cells of Henrietta Lacks, archived following her medical treatment in the 1950s. But today the publication of the whole genome sequence of one HeLa cell line raises novel is...
متن کاملCharacterization of adeno-associated virus genomes isolated from human tissues.
Infection with wild-type adeno-associated virus (AAV) is common in humans, but very little is known about the in vivo biology of AAV. On a molecular level, it has been shown in cultured cells that AAV integrates in a site-specific manner on human chromosome 19, but this has never been demonstrated directly in infected human tissues. To that end, we tested 175 tissue samples for the presence of ...
متن کاملFrom DNA to Genomes in 50 Years
quate to express the impact that these advances have Even in their wildest dreams, it seems unlikely that back had on science as we now know it. The Royal Society in 1953 Watson and Crick could have imagined how far meeting in London showcased the current status of DNA DNA science would develop in 50 years. We’ve come research. David Sherratt and Steve West organized a all the way from their in...
متن کاملParasitic nematodes - from genomes to control.
The diseases caused by parasitic nematodes in domestic and companion animals are major factors that decrease production and quality of the agricultural products. Methods available for the control of the parasitic nematode infections are mainly based on chemical treatment, non-chemical management practices, immune modulation and biological control. However, even with integrated pest management t...
متن کاملSNARE Proteins - From Membranes to Genomes
The function and the organization of eukaryotic cells require directional transport of vesicles between compartments. This sort of membrane flow relies on the presence of docking and fusion machinery. The core of this machinery is a protein complex composed of syntaxin, SNAP-25 and VAMP, collectively termed SNAREs. A correct interaction among SNARE prototypes is essential for fruitful docking a...
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ژورنال
عنوان ژورنال: G3 Genes|Genomes|Genetics
سال: 2013
ISSN: 2160-1836
DOI: 10.1534/g3.113.007443